Ready to plan a perfect getaway? Key West, Florida, is the ultimate tropical paradise. Filled with stunning beaches, vibrant coral reefs, and an array of activities for all ages – there’s something to suit everyone! From luxury resorts to family-friendly accommodations, travel enthusiasts can be sure to find a place that will make their vacation unforgettable. Look at these 10 luxury resorts in Key West, USA, that boast the perfect combination of comfort and style.

10 The Southernmost House Hotel

The Southernmost House Hotel is the perfect blend of historic charm and modern luxury, located in a prime location steps away from Key West's famous Duval Street. The hotel features 13 elegant guest rooms, each with unique decor and amenities such as free Wi-Fi, flat-screen TVs, iPod docks, and custom bath products.

Outside, guests can take a dip in the outdoor swimming pool or relax in the shaded hammocks and garden seating. Guests can also access a rooftop bar to enjoy breathtaking views of Key West's historic homes and landmarks.

9 Oceans Edge Resort & Marina Key West

Dive into paradise at Oceans Edge Resort & Marina Key West. This luxurious resort offers guests a serene island getaway with its plush accommodations, on-site marina, and an array of amenities. The hotel boasts 180 spacious guest rooms with modern furnishings and private balconies or patios.

Some rooms even have stunning views of the Gulf of Mexico. Guests can enjoy an array of onsite amenities such as a heated pool and Jacuzzi, a full-service spa and fitness center, and an onsite restaurant for delicious dining options.

8 Ocean Key Resort & Spa

Experience the ultimate in luxury and relaxation at Ocean Key Resort & Spa. This beachfront resort in Key West offers guests stunning views of the Gulf of Mexico and a variety of onsite amenities.

The guest rooms feature contemporary furnishings, designer linens, and modern decor. Guests can also enjoy access to the resort's two swimming pools, a luxury spa, a fitness center, and onsite dining. Additional amenities include a private beach, tennis court, and marina.

7 H2O Suites Hotel

Check out H2O Suites Hotel for a unique and luxurious experience. This boutique hotel offers guests an intimate atmosphere with its stylish decor and amenities. H20 Suites features 32 stylishly appointed guestrooms with imported furniture, granite countertops, and luxurious bathrooms.

Outside, guests can enjoy the outdoor swimming pool and Jacuzzi, as well as the fully stocked bar. Other amenities include a fitness center, business center, and onsite restaurant. The cuisine is a mix of flavorful American, Mexican and Caribbean cuisine.

  • Accommodation: H2O Suites Hotel
  • Address: 814 Duval St, Key West, FL 33040
  • Amenities: 32 stylishly appointed guestrooms, imported furniture, granite countertops, luxurious bathrooms, outdoor swimming pool and Jacuzzi, fully stocked bar, fitness center, business center, and onsite restaurant.

Related: Dive Capital Of The World: 10 Facts To Know About The Florida Keys

6 The Gardens Hotel

Discover a hidden oasis of tranquility at The Gardens Hotel. This beautiful property is on two acres of lush tropical gardens, offering guests the perfect place to relax and unwind. The hotel features 15 rooms, each with unique decor, antique furniture, and artwork.

Onsite amenities include an outdoor pool, fitness center, business center, and an onsite restaurant. Guests can also enjoy a complimentary breakfast every morning and complimentary Wi-Fi throughout the property.

  • Accommodation: The Gardens Hotel
  • Address: 526 Angela St, Key West, FL 33040
  • Amenities: 15 rooms, each with unique decor, antique furniture and artwork, outdoor pool, fitness center, business center, onsite restaurant, and complimentary breakfast every morning.

5 Pier House Resort & Spa

For an unforgettable beachfront getaway, check out Pier House Resort & Spa. This luxury resort is situated on Key West's beautiful Atlantic oceanfront and offers guests stunning ocean views and nearby islands. The resort boasts various luxurious rooms and suites, each featuring balconies or terraces and modern amenities.

Guests can enjoy the resort's various onsite amenities, such as its outdoor pool, full-service spa and fitness center, and onsite restaurant. Guests can also take advantage of the resort's private beach, boat charters, and water sports activities.

  • Accommodation: Pier House Resort & Spa
  • Address: 1 Duval St, Key West, FL 33040
  • Amenities: Luxurious rooms and suites, balconies or terraces and modern amenities, outdoor pool, full-service spa and fitness center, onsite restaurant, private beach, boat charters, and water sports activities.

4 The Marker Key West

Escape to The Marker Key West for a luxurious and memorable stay. This hotel is surrounded by the beautiful, crystal-clear waters of the Atlantic and the pristine white sands of Key West's beaches. Guests can choose from various stylish rooms and suites, each with its unique décor, contemporary amenities, and balconies or terraces.

The hotel offers a variety of onsite amenities, such as two outdoor swimming pools, a full-service spa and fitness center, an onsite restaurant and bar, and even private beach access. Other amenities include concierge services, a shuttle to and from Duval Street, and complimentary Wi-Fi throughout the property.

3 Hyatt Centric Key West Resort and Spa

Experience the best of Key West from the luxurious Hyatt Centric Key West Resort and Spa. This modern hotel offers guests a variety of stylishly appointed rooms and suites, each with its modern décor and amenities. Onsite amenities include an outdoor pool, fitness center, two onsite restaurants, and a full-service spa.

This main gate to the Florida Keys provides complimentary access to the beach and various activities such as snorkeling, sailing, and paddleboarding. Other services include a business center, concierge services, and complimentary Wi-Fi throughout the property.

2 The Marquesa Hotel

The Marquesa Hotel offers guests an unforgettable stay in the heart of Old Town Key West. This luxurious hotel is home to various rooms and suites, each with its unique décor. Onsite amenities include an outdoor pool, fitness center, gourmet onsite restaurant, bar, and a full-service spa.

Guests can take advantage of the hotel's complimentary beach access and onsite activities such as yoga, kayaking, and sailing. The Marquesa Hotel also offers concierge services, complimentary Wi-Fi throughout the property, and shuttle service to and from Duval Street.

  • Accommodation: The Marquesa Hotel
  • Address: 600 Fleming St, Key West, FL 33040
  • Amenities: Rooms and suites, an outdoor pool, fitness center, onsite gourmet restaurant, bar, full-service spa, complimentary beach access, concierge services, complimentary Wi-Fi, and shuttle service to and from Duval Street.

Related: 10 Unique South Florida Hotels With Gorgeous Rooftop Pools

1 Opal Key Resort & Marina

Opal Key Resort & Marina offers the perfect escape to paradise. This luxurious resort is located on an idyllic 10-acre island and offers stunning views of the Florida Keys. Guests can choose from various stylishly appointed rooms and suites, each with a private balcony or terrace.

Onsite amenities include an outdoor pool, fitness center, full-service spa, and two onsite restaurants. Other services include a private marina, complimentary Wi-Fi, concierge services, and shuttle service to and from Duval Street. Activities such as snorkeling, fishing, and kayaking are available to guests throughout their stay.